At least three explosions were heard after air strike sirens sounded in the Ukrainian capital, Kiev.
Mayor Vitaly Klitschko said the blast damaged residential buildings in the central Shevchenkivskii area.
Andriy Yarmak, the head of President Zelensky’s office, said the attack was carried out by so-called kamikaze drones.
The BBC’s Paul Adams, based in the city, said the explosions occurred around 7am local time on Monday.
Rescuers are on the scene and have asked residents to stay in air raid shelters.
Yarmak said the attack was from a kamikaze drone and Ukraine needs more air defense systems “as soon as possible.”
Russian President Vladimir Putin said last week’s attacks were in retaliation for the bombing of a key bridge linking Russia with occupied Crimea, which he blamed on Ukraine.
The center of Kiev was directly targeted for the first time during the war.
Earlier this week, Putin said there was no need for a more large-scale attack on Ukraine.
Most designated targets were hit, he said, not his aim to destroy the country.